ARSENAL SUBS: Mohamed Elneny, Willian, Hector Bellerin, Mat Ryan, Gabriel Magalhaes, Eddie Nketiah, Miguel Azeez, Reiss Nelson, Cedric Soares.
ARSENAL (4-2-3-1): Bernd Leno; Calum Chambers, Rob Holding, Pablo Mari, Bukayo Saka; Granit Xhaka, Thomas Partey; Nicolas Pepe, Dani Ceballos, Gabriel Martinelli; Alexandre Lacazette.
SHEFFIELD UTD (3-5-2): Aaron Ramsdale; John Egan, Ethan Ampadu, Enda Stevens; George Baldock, Oliver Norwood, John Lundstram, John Fleck, Ben Osborn; David McGoldrick, Oliver Burke.
Mikel Arteta has made five changes to his starting line-up, with Bellerin, Gabriel, Cedric, Smith Rowe and Willian missing from the side that drew in the Europa League in midweek. Chambers, Mari, Pepe, Ceballos and Martinelli all come into the team.